As US struggles to afford GLP-1 drugs, the rest of the world sees much lower prices.
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Middlemen play a part in virtually all industries in all countries. The idea that the very profitable companies producing these product are relegated to throwing up their hands in mock helplessness here is a red herring.I wish the article would go into more detail about why this is, and the role pharmacy benefit managers play in it.
I bet China and Europe does not have PBMs.
Nah, grab the gun from the guy poiinting it at you, shoot him, then shoot the other two.Oh sweet summer child… you hold both their heads under water.
Especially the people working extremely hard to make it complicated, so they could profit.Trump (1st term) - Nobody knew healthcare would be so complicated
Everyone - everyone knew
Just another front man in the Klown Kar. None of the problems will be fixed, but communicable vaccine-eradicable diseases will rise, as that really does not much affect the monied.Don't worry! With RFK jr in charge everything will be ...
Oh wait.
You're all fucked, sorry.
Not directly related, but you've inspired me.I'm guessing 90%+ of the Ars commentariat voted liberal, but burning things down is the opposite of what we want.
The NOVO CEO was interviewed by Senators a month ago. He testified that our drug prices are driven by the greedy Pharmaceutical Benefit Managers decisions. PBMs will limit or discontinue coverage to said drug because they aren't getting their 'piece of the pie'. He also provided an example of a drug that was discontinued because PBMs refused to cover the drug (due to the low return they were getting).
If this is just NOVO being greedy then why are ALL of our drug prices significantly higher than overseas? Like literally everything in the pharmacy is an order of magnitude more in the US than OUS?
EDIT: Interview for reference
View: https://www.youtube.com/watch?v=bAhpNRRkOFg
In Australia that is $31.60AUD for one pen.But how much Ozempic do $1350 buy you? In Mexico a single pen with up to six 0.25 shots is about $200, I'm not sure if it's really an apples to apples comparo.
Good thing I don't need that crap. Big Pharma is going for broke.
It's way more complicated than that. The reason there are no new antibiotics coming is because the economics don't favor developing them. So, while the US could certainly do something about how much we pay for drugs that exist now, there would be a pretty significant headwind toward new drug development, especially on anything remotely risky or small-market, unless something was also done about how costly it is to develop new medicine.The problem is that there's no way to negotiate a reasonable price.
The drug company would sell at any price that is above manufacturing price (which is practically zero).
The sustainable price to negotiate would be such that it would pay for the development, with a multiplier for the risk for drugs that don't work out, and some profit margin. It would be a lot more than manufacturing price, but a lot less than what it's being sold for - bulk of money made by pharmaceutical companies does not go towards R&D (and in case of new wall street darling pharma startups such as those headed by Vivek Ramaswamy, it is even worse with virtually zero R&D).
As an American out healthcare system sucks and is meant to maximize shareholders value... Not to benefit American health.It's kind of crazy how this suggests the US are effectively forcing European companies to up-charge their drugs for the American market. "Nope, you'll need to make it more expensive for us."
But from a capitalist point of view, of course it makes perfect sense. When you have a middleman who controls domestic distribution, they'll want a share of the pie. Bigger prices means a bigger pie, resulting in the same percentage generating a larger cut. Invest some of the profits into buying yourself a few Republican legislators to write laws blocking negotiation, and reap the benefits for your shareholders.
Spoiler: Europe doesn't to PBMs; negotiations are conducted directly between drug manufacturers and governments (the "Nanny State", as Republicans would call it), with insurers lobbying for discounts. The wild difference in pricing across the continent is still indicative of the pharma industry's own greed - it just seems the US enable a special kind of greed that serves as an additional multiplier on top of that.
Or perhaps rather enforcing a minimal level of greed, to have foreign companies match US manufacturers? "You must be at least this exploitative to enjoy the ride."
What? Are you some kinda commie? Next thing you know the government will own the roads, and the police and fire departments and then move on to internet and telecom infrastructure and sell access to service providers. Next they'll try to have a national electric grid. Its unfathomable but some socialist type people want the government to regulate businesses to encourage competition and drastically reduce anti-competitive corporate behavior. Corporate profits would plummet. Yacht and private jet sales would tank. Do you want to live in such a crazy world?American drugs should be somewhat more expensive than their developing world equivalents. That's price discrimination, and it's normal and healthy. But the difference shouldn't be by orders of magnitude. The case of Ozempic/Wegovy is also weird though because the underlying drugs are already fairly common and approved for use, but not for use as an obesity treatment.
Generally speaking I'd suggest that fixing the Medicare price of pharmaceuticals at no more than 50% above the OECD average would be a pretty reasonable control.
Well, according to the Senate testimony, the drug companies only see 26 cents on every dollar, the rest goes to middlemen. Reverse the percentages and American drugs suddenly cost a third of what they currently do, with no change to how drug development is financed. And a 26% cut for a new middleman would still be something even the Silicon Valley venture capitalists would most likely fund for billions. If you are even greedier than the platform bros...It's way more complicated than that. The reason there are no new antibiotics coming is because the economics don't favor developing them. So, while the US could certainly do something about how much we pay for drugs that exist now, there would be a pretty significant headwind toward new drug development, especially on anything remotely risky or small-market, unless something was also done about how costly it is to develop new medicine.
I'm 1000% in favor of heavy price regulation. I just don't want to give up the constant stream of miracles. And they are miracles - until these drugs literally nothing ever worked to deal with obesity in the main. People just stayed fat generally.
America basically subsidizes the rest of the world by overpaying, massively, for drugs. I'm not sure how exactly to fix that -- or if it's really broken.
And it is ultimately the American voter who is blame for it - if Americans are convinced out of supporting healthcare reform simply by someone uttering 'socialism' then all hope is pretty much lost at this stage. I mean, there are people right here right now in the year of our lord 2024 who believe that ObamaCare and the ACA are two different pieces of legislation - when you're dealing with that level of idiocy I don't hold out much hope things will change in the future.Just more proof that the American medical system is broken
And it is ultimately the American voter who is blame for it - if Americans are convinced out of supporting healthcare reform simply by someone uttering 'socialism' then all hope is pretty much lost at this stage. I mean, there are people right here right now in the year of our lord 2024 who believe that ObamaCare and the ACA are two different pieces of legislation - when you're dealing with that level of idiocy I don't hold out much hope things will change in the future.
You talk like things like that will be easy. Exactly what about complex supply hierarchies has ever been easy? At best, we can hope for (a non trump government) to exercise some override level control. At worst literally nothing can make the situation better.Well, according to the Senate testimony, the drug companies only see 26 cents on every dollar, the rest goes to middlemen. Reverse the percentages and American drugs suddenly cost a third of what they currently do, with no change to how drug development is financed. And a 26% cut for a new middleman would still be something even the Silicon Valley venture capitalists would most likely fund for billions. If you are even greedier than the platform bros...
It's not broken, it's doing exactly what it's supposed to do, keep "the poors" poorJust more proof that the American medical system is broken
So they should be pro vaccines then, right?Like most things, people care about what obviously and directly affects them personally.
It's way more complicated than that. The reason there are no new antibiotics coming is because the economics don't favor developing them. So, while the US could certainly do something about how much we pay for drugs that exist now, there would be a pretty significant headwind toward new drug development, especially on anything remotely risky or small-market, unless something was also done about how costly it is to develop new medicine.
I'm 1000% in favor of heavy price regulation. I just don't want to give up the constant stream of miracles. And they are miracles - until these drugs literally nothing ever worked to deal with obesity in the main. People just stayed fat generally.
America basically subsidizes the rest of the world by overpaying, massively, for drugs. I'm not sure how exactly to fix that -- or if it's really broken.
In a plutocratic oligarchy, big farma owns the government. So, not going to reign it in.This certainly will not get fixed under the new administration.
Its outrageous that the US doens't manage to reign in big farma on pricing. All this talk about how they will reduce inflation and not even an intent to act where it truly matters.
It's actually $451.02 + $9.73 = $460.75 or $329.44USD at this morning's spot rate.This is wrong, it is actually $400
https://www.cbc.ca/radio/thecurrent/wegovy-obesity-funding-ozempic-1.7222776
I think the Danes just don’t like the USATurns out the Danes are not the vilified socialists they are portraied to be. Thank god they are proper capitalists instead.
It's way more complicated than that. The reason there are no new antibiotics coming is because the economics don't favor developing them. So, while the US could certainly do something about how much we pay for drugs that exist now, there would be a pretty significant headwind toward new drug development, especially on anything remotely risky or small-market, unless something was also done about how costly it is to develop new medicine.
I'm 1000% in favor of heavy price regulation. I just don't want to give up the constant stream of miracles. And they are miracles - until these drugs literally nothing ever worked to deal with obesity in the main. People just stayed fat generally.
America basically subsidizes the rest of the world by overpaying, massively, for drugs. I'm not sure how exactly to fix that -- or if it's really broken.
It's not even a slightly dubious assumption - it's a well established fact.Even assuming what you've written is true, (which is a VERY dubious assumption)
Nobody is blaming foreigners - the net effect of overpaying systemically means that other countries get a free ride. It's not like they clubbed together to make it happen, they just took advantage of an obvious arbitrage like anyone does.That isbullshitfactually incorrect.
All the extra money is going to middlemen - and drug companies spend much more on marketing than R&D.
So you suckers aren't subsidising the rest of the world, you're just enriching rent-seeking parasites and the politicians they bribe.
In other words, the system is behaving exactly as designed.
This is what you've voted for yourselves for decades, no need to blame foreigners.
Well, sort of! The problem I have with your conclusion is that you cannot point to any successful counterexample ever. It's not like the People's Republic of China is a fount of amazing new medicine. It may be, in time -- but it isn't today. Importantly too the only reason the PRC is even remotely an interesting case is they stopped acting like a differently flavored version of the USSR, and started using some market based approaches. Their flavor is interesting, but I sure wouldn't rather live there.Even assuming what you've written is true, (which is a VERY dubious assumption) all that demonstrates is that a free market is the worst possible approach to health care. New antibiotics are desperately needed, so if a free market doesn't value that, it's a problem with the market, not the need.
i think, when Lex Friedman interviewed Mark Cuban this issue was not small part of the conversation.Well...why? It would be nice to see some data at how those prices are arrived at across various countries. All we have is that China does not subsidize, but does anyone else? Is US demand simply that outrageous, or is Novo ripping everyone off? Is there some sort of hyper-expensive regulatory fee that is due in the US?
It is difficult to see how our price isn't in line with China's if they truly offer no subsidies of any kind.
"I'm going to make you an offer that you can't refuse."
I lost all respect for Bernie with that whole dog and pony show. It is a distraction, he knows why our system is fucked. And he knows that our government is too incompetent and corrupt to resolve it. So he misdirects to a foreign company (and completely glosses over the fact US based pharmaceutical companies screw American citizens just as bad).What lazy journalism from Beth Mole who is usually on point. The Senate hearing was laughable as Bernie got righteous and fiery only to be shut down by CEO Jorgenson saying "it's not our company setting the price, it's the PBMs in your healthcare system". Every country in the world will get GPL-1 drugs cheaper than the US as they do with every other drug i.e. Insulin. Capitalism in healthcare is scary...
Found the person who has never been to China but eats up their propaganda... Lol.The Chinese don't need it anyway. Most of them eat fresh farm to market food, so they are not overweight and generally much healthier.
How can you even say that? We will eventually have a true medical expert who is also an expert connoisseur of road kill, former long term heroin addict, and a brain worm personal housing developer. As well as an accomplished anti-vaxxer who contributed to the deaths of dozens of children in American Samoa. What could possibly go wrong? This even ignores his recent Froot Loops fiasco, and his always wanting to get the “chemicals” out of food and water.This certainly will not get fixed under the new administration.