Carnivorous oyster mushrooms can kill roundworms with “nerve gas in a lollipop”

Unclebugs

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I've read several articles in Ars about the extraordinary mechanisms that various lifeforms employ to defend, hunt, and or consume other organisms. Every time I read one I think to myself that I am reading another plot device for a horror movie. We are so used to the predator chasing the prey, or a standard sort of infection treatable by an antibiotic. It almost makes the aliens in the movie predator seem primitive or unimaginative. I really love the one where the fungus takes over the brain of an insect turning it into a puppet which almost makes zombies plausible.
 
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Joel from the last of us has entered the chat. He had this to say about the article:

Reading this article brings back some difficult memories for me. Seeing how these oyster mushrooms can kill roundworms with "nerve gas in a lollipop" just reminds me of the devastation that the fungal outbreak caused in my world. It's amazing the ways that nature can adapt and evolve, but it's also a harsh reminder of how deadly it can be. It makes me wonder if the same thing could happen in our world and how we would survive. It's a sobering thought.
 
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Oyster mushroom fungus will eat anything. I grow them on used coffee grounds. Like, nothing else, just used great value coffee grounds that any sane person would trash. Oyster mushrooms love it. You can get a starter mycelium off the bottom of mushrooms you buy at the store. Look for fluffy white fuzz at the roots.
 
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As nematodes a bane to tomato gardens, I'm wondering if there's an exploit for gardeners?
You could have a win‑win there – both control some pests and later harvest some delicious mushrooms. Though it might backfire as well – aren't some non‑plant‑eating nematodes used as a biological pest control themselves?
 
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SimonW

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Wonder what 3-octanone from those mushrooms does in the human system? And since they’re volatile, I’m assuming cooking/sautéing the mushrooms lowers the toxicity profile?
You can also find it in nectarines and in some perfumes. So now you know what to eat and spray yourself with if you want to keep the roundworms at bay
 
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Xenobio

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As nematodes a bane to tomato gardens, I'm wondering if there's an exploit for gardeners?
If you want to do biological pest control you're probably better off buying some predatory nematodes that eat other nematodes and sprinkling them in your tomato bed. I don't have a garden but I used them in house plants for fungus gnats. The brand I bought is Nature's Good Guys - website has some information on picking the right species for the right task, or they also sell a mixture.
 
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Robscura

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Many comments here seem to reflect a common misconception regarding mushrooms.

What we call a mushroom is only the fruiting/sporulating portion of the fungus. The hyphae and their toxocysts referred to in the article would be the portion of the fungus colonizing the wood itself, somewhat analogous to roots of a tree.

The hyphae can have different chemical/physical properties than the fruit. I don't see anything in the article suggesting that the fruits of the oyster mushroom are toxic, regardless.
 
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PhaseShifter

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PhaseShifter

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Wonder if there’s any application. These things are dead simple to grow if you have any capacity for sterile technique at all. They can top fruit in bottles, so automation is pretty straightforward as well.
Plus, you can drop $15-20 for a grow kit, and extend its life by tearing the block apart and mixing in used coffee grounds from time to time.
 
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Hmm...no one seems to be asking the question: Are these useful as a therapeutic in some way for humans who get roundworm infections? Any guesses?
I'd just say that if you have oyster mushroom mycelia growing under your skin or in your lungs and liver for any roundworms to nibble on, you got some more serious problems than roundworms...
 
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Oak

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Hmm...no one seems to be asking the question: Are these useful as a therapeutic in some way for humans who get roundworm infections? Any guesses?

I'd just say that if you have oyster mushroom mycelia growing under your skin or in your lungs and liver for any roundworms to nibble on, you got some more serious problems than roundworms...

Har, but I agree with bkaral -- an obvious question is whether high doses of 3-octanone would be safe for people, and if so, could serve well as a new anthelmintic.

Though I wonder if the tolerance (that some people have mentioned here) for its presence in food might be due to rapid breakdown in the human body, which could limit its usefulness internally.
 
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